Protein Modification Reagents
Cayman Chemical mal-PEG2-AZD 50mg
A bioconjugation linker; has been used in the development of protein- and peptidomimetic-antibody conjugates
Medchemexpress LLC 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo | 1263045-16-4 | 99.8% | 500 MG
Mal-amido-PEG4-acid is an off-white to yellow solid with a molecular formula of C18H28N2O9 and a molecular weight of 416.42. It exhibits a high purity of 99.76% as determined by HPLC analysis, and its 1H NMR and LCMS spectra are consistent with the chemical structure.
- Off-white to yellow solid appearance
- Molecular formula C18H28N2O9
- Molecular weight 416.42
- Purity of 99.76% (HPLC)
- NMR and LCMS data consistent with structure
- Store at -20°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
Broadpharm Bromo-PEG3-CH2CO2tBu | 2100306-71-4 | MFCD30723231 | 500mg
Bromo-PEG3-CH2CO2tBu | Putity: 98% | MW: 327.2 | 2100306-71-4 | MFCD30723231 | 500mg
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 100 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules 882847-34-9 | FmocNH-PEG6-CH2CH2COOH | Acrotein ChemBio Inc. | MFCD06656474 | 575.655 | C30H41NO10 | 97.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 487561647
FmocNH-PEG6-CH2CH2COOH | Acrotein ChemBio Inc. | 882847-34-9 | MFCD06656474 | 575.655 | C30H41NO10 | 97.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 487561647
Medchemexpress LLC (S,R,S)-AHPC-PEG2-N3 | 2010159-45-0 | 99.9% | 601.72 g/mol | C28H39N7O6S | 5 MG
(S,R,S)-AHPC-PEG2-N3 is an E3 ligase ligand-linker conjugate bearing a terminal azide for click chemistry, used as a building block in PROTAC synthesis and bioconjugation.
- Terminal azide enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- Two-unit PEG linker provides solubility and spacer functionality.
- Designed for conjugation to alkyne, DBCO, or BCN functional partners.
- Supplied in small-quantity formats for research and synthesis workflows.
- Molecular weight 601.72 g/mol; molecular formula C28H39N7O6S.
Medchemexpress LLC Biotin-PEG11-Mal | 1646619-56-8 | 96.5% | C41H71N5O16S | 25 MG
Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs themselves consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. These molecules function by harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- PROTACs consist of two distinct ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Functions by harnessing the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Gly-gly-gly-PEG4-DBCO | 2353409-80-8 | 95.1% | 694.77 g/mol | C35H46N6O9 | 5 MG
Gly-gly-gly-PEG4-DBCO is a 4-unit polyethylene glycol (PEG) linker bearing a dibenzocyclooctyne (DBCO) moiety used for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition, SPAAC) in bioconjugation workflows such as antibody-drug conjugate synthesis. It is supplied as a solid in small-mass vials for research use.
- 4-unit PEG linker enabling flexible spacing in conjugates.
- DBCO moiety for SPAAC (copper-free click) with azide-containing partners.
- Suitable for antibody-drug conjugate synthesis and general bioconjugation.
- Solid, light yellow to yellow appearance for convenient handling.
- Reported purity 95.1% supports research-grade applications.
Medchemexpress LLC 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)- | 1255942-07-4 | 99.49% | 50 MG
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative that contains a biotin group and four PEG units. It functions as a versatile biotinylation reagent, enabling the introduction of a biotin moiety to azide-labeled biomolecules. This process occurs through a copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction. It is a click chemistry reagent, featuring a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
- Azadibenzocyclooctyne-biotin derivative
- Contains a biotin group and 4 PEGs
- Versatile biotinylation reagent
- Used for introducing a biotin moiety to azide-labeled biomolecules
- Utilizes copper-free strain-promoted alkyne-azide click chemistry (SPAAC)
- Contains a DBCO group for SPAAC with azide groups
- For research use only
eMolecules 198227-38-2 | t-Boc-N-amido-PEG15-amine | Broadpharm | MFCD28385469 | 821.012 | C37H76N2O17 | 95.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 296213670
t-Boc-N-amido-PEG15-amine | Broadpharm | 198227-38-2 | MFCD28385469 | 821.012 | C37H76N2O17 | 95.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 1g | 296213670
Medchemexpress LLC 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-Pentadecaoxahexatetracontan-46-amine | 2745717-94-4 | 99.9% | 691.85 | 50 MG
The m-PEG15-amine is a chemical compound with the molecular formula C31H65NO15 and a molecular weight of 691.85. It is provided as a colorless to light yellow oil with a purity of 99.91%. This product is intended for use as a laboratory chemical and in the manufacture of substances. It is classified as hazardous, causing acute oral toxicity, skin and serious eye irritation, and potential respiratory tract irritation.
- Consistent with structure based on ¹H NMR Spectrum and LCMS
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Medchemexpress LLC Propargyl-PEG4-CH2COOH | 1429934-37-1 | >97.0% | 290.31 | 25 MG
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide-containing molecules. PROTACs, composed of two ligands linked together, target an E3 ubiquitin ligase and a specific protein, thereby utilizing the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features Alkyne group for CuAAc
- Enables selective protein degradation via ubiquitin-proteasome system
Medchemexpress LLC Biotin-PEG11-Mal | 1646619-56-8 | 96.5% | C41H71N5O16S | 50 MG
Biotin-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes E3 ubiquitin ligase and target protein ligands
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Dde Biotin-PEG4-DBCO | 1807512-43-1 | 96.2% | C47H61N5O9S | 25 MG
Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains a DBCO group that undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with azide-containing molecules
Medchemexpress LLC Mal-amido-PEG5-C2-NHS ester | 1315355-92-0 | >=98.0% | 557.55 g/mol | C24H35N3O12 | 1 G
Mal-amido-PEG5-C2-NHS ester is a non-cleavable PEG-based linker containing a maleimide and an N-hydroxysuccinimide (NHS) ester for conjugation to thiol and amine groups in proteins, peptides, and oligonucleotides. It is commonly used in antibody-drug conjugate (ADC) synthesis and other bioconjugation research applications.
- Contains maleimide and NHS ester functional groups
- Non-cleavable PEG-based linker for bioconjugation
- CAS number 1315355-92-0
- Molecular weight 557.55 g/mol
- Formula C24H35N3O12
- Appearance viscous liquid, colorless to light yellow
- Purity >=98.0%
- Storage pure form -20°C; in solvent -80°C (6 months) or -20°C (1 month)
- Available in 1 G package